Dr Vincent Bizet

Vincent Bizet studied chemistry at the University of Caen (FR) and then moved to the INSA of Rouen (FR) to do his PhD under the supervision of Dr. D. Cahard (2009-2012). After postdoctoral studies at RWTH Aachen University  (DE) with Prof. C. Bolm (2013-2014) and then at Geneva University (CH) with Prof. C. Mazet (2014-2016), he joined the CNRS as “Chargé de recherche” at the University of Strasbourg (FR) in 2016 in the team “Biomolecules, Synthesis and Methodologies” (BSM) led by Dr. N. Blanchard from the “Laboratoire d’Innovation Moléculaire et Applications” (LIMA, UMR 7042). 
LinkedIn ORCID 0000-0002-0870-1747
  (+33) 3 89 33 68 38
Short CV:  
Research topics:
His research interest currently focus on the development of new synthetic methodologies with a special focus on tansition metal-catalyzed transformations.
– training correspondent of the research unit
– Master 1-S1: Catalysis
Nb of publication: 30          Nb of book chapter: 1          Citations: >1000          H-index = 17
List of publications:
30) Synthesis and Physicochemical Properties of 2-SF5-(Aza)Indoles, a New Family of SF5 Heterocycles
Debrauwer, V.; Leito, I.; Lõkov, M.; Tshepelevitsh, S.; Parmentier, M.; Blanchard, N.; Bizet, V. ACS Org. Inorg. Au 2021, DOI: 10.1021/acsorginorgau.1c00010
29) Ligand-Controlled Regiodivergent PalladiumCatalyzed Hydrogermylation of Ynamides
Debrauwer, V.; Turlik, A.; Rummler, L.; Prescimone, A.; Blanchard, N.; Houk, K. N.; Bizet, V. J. Am. Chem. Soc. 2020, 142, 11153-11164.
Highlighted in:  Actualités de l’INC CNRS, 9 octobre 2020 (link).
28) Pentafluorosulfanyl chloride  
Burton, D. J; Wang, Y.; Bizet, V.; Cahard, D. e-EROS Encyclopedia of Reagents for Organic Synthesis. Wiley, 2020, DOI:10.1002/047084289X.rn00413.pub2.
27) Optimized Synthesis of 7-Azaindazole by a Diels–Alder Cascade and Associated Process Safety
Brach, N.; Le Fouler, V.; Bizet, V.; Lanz, M.; Gallou, F.; Bailly, C.; Hoehn, P.; Parmentier, M.; Blanchard N.  Org. Process Res. Dev. 2020, 24, 776-786.
26) Activating Pyrimidines by Pre-distortion for the General Synthesis of 7-Aza-indazoles from 2-Hydrazonylpyrimidines via Intramolecular Diels–Alder Reactions
Le Fouler, V.; Chen, Y.; Gandon, V.; Bizet, V.; Salomé, C.; Fessard, T.; Liu, F.; Houk, K. N.; Blanchard N.  J. Am. Chem. Soc. 2019, 141, 15901-15909.
25) Acid Fluorides in Transition‐Metal Catalysis: A Good Balance between Stability and Reactivity
Blanchard N.; Bizet, V.  Angew. Chem. Int. Ed. 2019, 58, 6814-6817.
24) Diels–Alder and Formal Diels–Alder Cycloaddition Reactions of Ynamines and Ynamide
Duret, G.; Le Fouler, V.; Bisseret, P.; Bizet, V.; Blanchard N. Eur. J. Org. Chem 2017, 6816-6830.
23) Mechanistic Investigation of the Pd-Catalyzed Intermolecular Carboetherification and Carboamination of 2,3-Dihydrofuran: Similarities, Differences and Evidence for Unusual Reaction Intermediates
Borrajo Calleja, G. M.; Bizet, V.; Besnard, C.; Mazet C.  Organometallics 2017, 36, 3553-3563.
22) Influence of the dissolution solvent on the cytotoxicity of octahedral cationic Ir(III) hydride complexes
Huang, H.; Humbert, N.; Bizet, V.; Patra, M.; Chao, H.; Mazet, C.; Gasser G. J. Organomet. Chem. 2017, 839, 15-18.
21) Direct Access to Furoindolines by Palladium-Catalyzed Intermolecular Carboamination
Bizet, V.; Borrajo Calleja, G. M.; Besnard, C.; Mazet C. ACS Catal. 2016, 6, 7183-7187.
Highlighted in: Synfacts
2016, 12, 1257 (link).
20) Palladium Catalyzed Enantioselective Intermolecular Carboetherification of Dihydrofurans
Borrajo Calleja, G. M.; Bizet, V.; Mazet C. J. Am. Chem. Soc. 2016, 138, 4014-4017.
Highlighted in: Synfacts
2016, 12, 591 (link).
19) Access to Enantioenriched 2,3- and 2,5-Dihydrofurans With a Fully substituted C2 Stereocenter by Pd-Catalyzed Asymmetric Intermolecular Heck Reaction
Borrajo Calleja, G. M.; Bizet, V.; Bürgi, T.; Mazet C. Chem. Sci. 2015, 6, 4807-4811.
Highlighted in: Synfacts
2015, 10, 1075 (link).
18) Sulfur Imidations: Access to Sulfimides and Sulfoximines
Bizet, V.; Hendrix, C. M. M.; Bolm, C. Chem. Soc. Rev. 2015, 44, 3378-3390.
17) Direct Access to N-Alkyl Sulfoximines from Sulfides by a Sequential Imidation/Oxidation Procedure
Dannenberg, C. A.; Bizet, V.; Bolm, C. Synthesis 2015, 47, 1951-1959.
16) Sulfur Imidations by Light-Induced Ruthenium-Catalyzed Nitrene Transfer Reactions
Bizet, V.; Bolm, C. Eur. J. Org. Chem. 2015, 2854-2860.
15) Transition-Metal-Free Oxidative Iodination of 1,3,4-Oxadiazoles
Dannenberg, C. A.; Bizet, V.; Zou, L. H.; Bolm, C. Eur. J. Org. Chem. 2015, 77-80.
14) Methionine and Buthionine Sulfoximine: Syntheses under Mild and Safe Imidation/Oxidation Conditions
Buglioni, L.; Bizet, V.; Bolm, C. Adv. Synth. Catal. 2014, 356, 2209-2213.
13) Fluorine as a Control Element in Asymmetric Synthesis
Bizet, V.; Cahard, D. Chimia 2014, 68, 378-381.
12) Light-Induced Ruthenium-Catalyzed Nitrene Transfer Reactions: A Photochemical Approach towards N-Acyl Sulfimides and Sulfoximines
Bizet, V.; Buglioni, L.; Bolm, C. Angew. Chem. Int. Ed. 2014, 53, 5639-5642.
11) Fluorinated sulfoximines : syntheses, properties and applications
Bizet, V.; Kowalczyk, R.; Bolm, C. Chem. Soc. Rev. 2014, 43, 2426-2438.
10) Recent progress in asymmetric fluorination and trifluoromethylation reactions
Bizet, V.; Besset, T.; Ma, J.-A.; Cahard, D. Curr. Top. Med. Chem. 2014, 14, 901-614.
9) The influence of fluorine in asymmetric catalysis
Bizet, V.; Cahard, D. Chem. Soc. Rev. 2014, 43, 135-147.
8) Iron (II) complexes are suitable catalysts for the isomerization of trifluoromethylated allylic alcohols. Synthesis of trifluoromethylated dihydrochalcones
Cahard, D.; Bizet, V.; Dai, X.; Gaillard, S.; Renaud, J.-L. J. Fluorine Chem. 2013, 155, 78-82.
7) Isomérisation rédox : une réaction économe en atomes à fort potentiel d’innovation
Bizet, V.; Cahard, D.; Gaillard, S.; Renaud, J.-L. Les Techniques de l’Ingénieur 2013, IN 159.
6) Ruthenium-catalyzed one-pot tandem isomerization–transfer hydrogenation reactions of γ-trifluoromethylated allylic alcohols and β-trifluoromethylated enones
Bizet, V.; Pannecoucke, X.; Renaud, J.-L.; Cahard, D. Adv. Synth. Catal. 2013, 355, 1394-1402 (Corrigendum 2013, 355, 2113).
5) Synthesis of β-CF3 ketones from trifluoromethylated allylic alcohols by ruthenium catalyzed isomerization
Bizet, V.; Pannecoucke, X.; Renaud, J.-L.; Cahard, D. J. Fluorine Chem. 2013, 152, 56-61.
4) N-Fluorobenzensulfonimide
Bizet, V. Synlett 2012, 23, 2719-2720.
3) Ruthenium catalyzed redox isomerization of trifluoromethylated allylic alcohols: mechanistic evidence for an enantiospecific pathway
Bizet, V.; Pannecoucke, X.; Renaud, J.-L.; Cahard, D. Angew. Chem. Int. Ed. 2012, 51, 6467-6470.
Highlighted in: CNRS, en direct des laboratoires de l’institut de chimie (Link).
2) Synthesis of α-CF3-substituted carbonyl compounds with relative and absolute stereocontrol using electrophilic CF3-transfer reagents
Matoušek, V.; Togni, A.; Bizet, V.; Cahard, D. Org. Lett. 2013, 13, 5762-5765.
1) Metal-Free SN2′ Decarboxylative Rearrangement of β-Keto Esters
Bizet, V.; Lefebvre, V.; Baudoux, J.; Lasne, M.-C.; Boulangé, A.; Leleu, S.; Franck, X.; Rouden, J. Eur. J. Org. Chem. 2011, 4170-4175.
List of book chapters:
1) Asymmetric fluorination methods and their application for the stereoselective synthesis of fluorinated drugs
Bizet, V.; Cahard, D. in “Stereoselective Synthesis of Drugs and Natural Products” (Chapter 44), Ed. Wiley-Blackwell. 2013, ISBN: 978-1-1180-3217-6, pp. 1347-1376.